Apolipoprotein B (ApoB)

Apolipoprotein B (apoB) reflects the total number of atherogenic lipoprotein particles in circulation, including LDL, VLDL, IDL, and Lp(a), with each particle carrying a single apoB molecule. This makes apoB a direct measure of particle number and a more accurate indicator of cardiovascular health. The National Lipid Association recognizes apoB as superior to LDL-C for cardiovascular risk assessment, particularly in the case of discrepancies between cholesterol content and particle concentration. Individuals with high apoB demonstrate lower cardiovascular health than those with similar LDL-C levels but lower apoB measurements. [42] [43]

Apolipoprotein B (ApoB) VMR Male Apolipoprotein B (ApoB) RR Male Apolipoprotein B (ApoB) VMR Female Apolipoprotein B (ApoB) RR Female


[42]Soffer DE, Marston NA, Maki KC, et al. Role of apolipoprotein B in the clinical management of cardiovascular risk in adults: An Expert Clinical Consensus from the National Lipid Association. J Clin Lipidol. 2024;18(5):e647-e663. doi:10.1016/j.jacl.2024.08.013


[43]Zubiran R, Remaley AT. Current opinions on the role of apolipoprotein B in the clinical management of cardiovascular risk. Future Cardiol. Published online July 16, 2025:1-3. doi:10.1080/14796678.2025.2535184

© 2026 Volo Health, LLC. All rights reserved. VOLO™ is a trademark of Volo Health, LLC. All other trademarks, service marks, trade names, and logos are the property of their respective owners.